A clinico-pathological study of coronary disease.
نویسندگان
چکیده
In a previous paper (Snow et al., 1955) the pathological findings in the hearts of twenty-five patients with coronary disease were described. In the present paper these findings, together with those in an additional seven patients, are correlated with the clinical features. Material. Thirty-two patients were studied, all with clinical evidence of ischaemic heart disease. Those in whom hypertension or valvular lesions may have contributed to the ischkmic symptoms were not excluded. Sixteen of the patients had been under the care of the Department of Cardiology and all had been observed personally by one of us; 11 had been under the care of other units of Manchester Royal Infirmary, and 5 had been admitted to Crumpsall Hospital, Manchester. Only cases with a full clinical history were included in the series, which was not consecutive. Symptoms occurring within three months of death were the main basis of this study since up to this time the age of a myocardial infarct can be estimated pathologically and correlated chronologically with the clinical events. At necropsy the coronary arteries were injected with a radiopaque medium and radiographed to locate all occlusions; the myocardium was then serially sectioned and all lesions examined histologically by the technique previously described (Snow et al., 1955).
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عنوان ژورنال:
- British heart journal
دوره 18 4 شماره
صفحات -
تاریخ انتشار 1956